Intraflagellar Transport
Info Page Total Peptides Axo Count M+M Count KCl Count Terg Count TM Helices, Lipid Mod 30 Min DeFlag (Fold Δ) XAP5 (Fold Δ) Human Homolog Gene and Aliases ChlamyFPv5 Annotation References: O. Vallon Description
Cre06.g250300.t1.2 82 0 78 4 0 0 4.28 DYNC2H1 DHC16; DHC1b DHC16 (DHC1b), Cytoplasmic Dynein 1b Heavy Chain (Pazour et al. Witman 1999)(Porter et al. Dentler 1999)(Hom et al. King 2011); Ciliary level increases during disassembly (Wang et al. Pan 2017) DHC16  |  Homologue of mammalian cytoplasmic dynein 2 heavy chain. Motor for retrograde intraflagellar transport. Not an inner arm dynein. Upregulated upon deflagellation by nearly 8-fold; null-allele mutant was isolated (PMID 29743196)
Cre17.g703900.t1.2 36 0 33 2 1 0 9.46 -2.19 IFT172 IFT172; SLB IFT172, Intraflagellar Transport Protein 172 (Cole et al. Rosenbaum 1997)(Pedersen et al. Rosenbaum 2005)(Follit et al. Pazour 2009)(Cole 2003); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT172  |  Component of peripheral subcomplex of IFT-B particle; contains WD40 and TPR repeats
Cre01.g027950.t1.2 29 0 27 2 0 0 7.29 -1.68 IFT74 IFT74; IFT72; IFT71; CMG1 IFT74, Intraflagellar Transport Protein 74 (Follit et al. Pazour 2009)(Lucker et al. Cole 2005)(Cole 2003)(Iomini et al. Piperno 2004)(Bhogaraju et al. Lorentzen 2013)(Kubo et al. Witman 2016)(Brown et al. Witman 2015); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT74  |  Component of core of IFT-B particle
Cre13.g572700.t1.2 20 0 19 1 0 0 8.81 -1.3 WDR19 IFT144; FAP66; FLA15 IFT144 (FAP66), Intraflagellar transport protein 144 (Cole 2003)(Iomini et al. Dutcher2009); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT144  |  Flagellar Associated Protein, component of core of IFT-A particle; found in the flagellar proteome [PMID: 15998802]
Cre06.g268800.t1.2 19 0 18 1 0 0 5.77 -1.11 TTC21B IFT139; FAP60; FLA17 IFT139 (FAP60), Intraflagellar transport protein 139 (Cole 2003)(Iomini et al. Dutcher2009); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT139  |  Flagellar Associated Protein, component of IFT-A particle; found in the flagellar proteome [PMID: 15998802]
Cre08.g362650.t1.1 19 0 19 0 0 0 9.81 IFT140 IFT140 IFT140, Intraflagellar Transport Protein 140 (Jonassen et al. Pazour 2012)(Cole 2003); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT140  |  Component of core of IFT-A particle
Cre17.g723600.t1.2 17 0 16 1 0 0 5.3 -1.81 IFT81 IFT81; FLA9 IFT81, Intraflagellar Transport Protein 81 (Sun et al. Hopkins 2004)(Lucker et al. Cole 2005)(Follit et al. Pazour 2009)(Cole 2003)(Bhogaraju et al. Lorentzen 2013)(Kubo et al. Witman 2016); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT81  |  Component of core of IFT-B particle
Cre12.g522550.t1.2 17 0 11 4 2 0 6.22 -1.29 KIF3A FLA8; KIN2-1 FLA8, Kinesin II Motor Protein (Miller et al. Dutcher 2005)(Cole et al. Rosenbaum 1997); Ciliary level increases during disassembly (Wang et al. Pan 2017) FLA8  |  Kinesin heavy chain, kinesin-2 (KRP85/95) family; probable subunit of kinesin-II, the anterograde motor for intraflagellar transport
Cre17.g730950.t1.2 17 0 12 3 2 0 5.01 -1.79 KIF3A FLA10; KIN2-2 FLA10, Kinesin-II Motor Protein (Walther et al. Hall 1994)(Cole et al. Rosenbaum 1997); Ciliary level increases during disassembly (Wang et al. Pan 2017) FLA10  |  kinesin-2 (KRP85/95) family; motor subunit of heterotrimeric kinesin complex that drives anterograde intraflagellar transport
Cre17.g721250.t1.2 14 0 14 0 0 0 6.5 CLUAP1 IFT38; FAP22; Qilin; Dyf-3; Cluap1; CFAP22 IFT38 (FAP22 | Qilin | Dyf-3), Intraflagellar Transport Protein 38 (Ou et al. Scholey)(Follit et al. Pazour 2009); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT38  |  Found in the flagellar proteome; component of IFT-B peripheral subcomplex; similar to clusterin-associated protein 1 CLUAP1 and cystic kidney disease gene qilin
Cre01.g065822.t1.1 12 0 11 1 0 0 6.13 -1.44 IFT122 IFT122; FAP80 IFT122 (FAP80), Intraflagellar Transport Protein 122 (Cole 2003); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT122  |  NULL
Cre07.g335750.t1.1 11 0 11 0 0 0 9.44 IFT88 IFT88 IFT88, Intraflagellar Transport Protein 88 (Pazour et al. Cole 2000)(Pazour et al. Besharse 2002)(Follit et al. Pazour 2009)(Cole 2003); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT88  |  Component of core of IFT-B particle
Cre11.g467739.t1.1 11 0 11 0 0 0 6.91 TRAF3IP1 IFT54; FAP116; Dyf-11; Elipsa; Traf3ip1 IFT54 (FAP116 | Dyf-11 | Elipsa), Intraflagellar Transport Protein 54 (Follit et al. Pazour 2009); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT54  |  belongs to peripheral subcomplex of IFT-B particle; similar to human TRAF3IP1
Cre11.g475000.t1.1 10 0 8 2 0 0 8.76 -1.04 WDR35 IFT121; FAP118; IFT122B IFT121 (FAP118 | IFT122B), Intraflagellar Transport Protein 121 (Cole 2003); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT121  |  Flagellar Associated Protein, found in the flagellar proteome [PMID: 15998802]; component of IFT-A particle; identified in the flagellar basal body proteome as FBB1 [PMID: 15137946]; upregulated by deflagellation
Cre09.g398882.t1.1 10 0 7 3 0 0 5.32 -1.76 DYNC2LI1 DLI1; D1bLIC DLI1 (D1bLIC), Dynein 1b Light Intermediate Chain D1bLIC (Perrone et al. Porter 2003)(Hou et al. Witman 2004); Ciliary level increases during disassembly (Wang et al. Pan 2017) DLI1  |  NULL
Cre10.g428664.t1.1 9 0 9 0 0 0 5.27 -1.42 WDR60 DIC6; FAP163; D1bIC1; WD60 DIC6 (FAP163 | D1bIC1|mammalian WD60), Dynein 1b Intermediate Chain IC1 (Patel-King et al. King 2013 ); Ciliary level increases during disassembly (Wang et al. Pan 2017) DIC6  |  NULL
Cre02.g110950.t1.1 8 0 1 7 0 0 6.55 WDR34 DIC5; FAP133; D1bIC2; WD34 DIC5 (FAP133 | D1bIC2 | WD34), WD-Repeat Intermediate Chain of Dynein 1b (Rompolas et al. King 2007)(Hom et al. King 2011); Ciliary level increases during disassembly (Wang et al. Pan 2017) DIC5  |  found in the flagellar proteome
Cre03.g204150.t1.2 7 0 6 1 0 0 8.87 -2.18 IFT80 IFT80; FAP167 IFT80 (FAP167), Intraflagellar Transport protein 80 (Follit et al. Pazour 2009)(Cole 2003)(Taschner et al. Lorentzen 2018); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT80  |  Component of peripheral subcomplex of IFT-B particle
Cre10.g467000.t1.2 7 0 7 0 0 0 4.2 -1.18 IFT57 IFT57 IFT57, Intraflagellar Transport Protein 57 (Pazour et al. Besharse 2002)(Follit et al. Pazour 2009)(Cole 2003); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT57  |  Component of peripheral subcomplex of IFT-B particle
Cre03.g181150.t1.1 7 4 2 1 0 0 7.66 DYNLL1 ; DYNLL12 DLL1; ODA-LC8; RSP22; FLA14 DLL1 (ODA-LC8 | RSP22), Light Chain Associated with Outer Arm Dynein, Cytoplasmic Dynein 1b, Inner Arm Dynein I1/f and Radial Spokes (Pazour et al. Witman 1998)(King et al. Patel-King 1995 ) (Hom et al. King 2011)(Yang et al. Witman 2006)(Schmidts et al. Witman 2015); The mutation in PF5 strain CC1331 is allelic to DLL1 but the mutation in PF5 strain CC1028 is not allelic. The defective gene in CC1028, presumptive to be the bona fide PF5, remains to be identified (Pinfen Yang). FLA14  |  LC8 component of outer arm dynein, inner arm I1/f and RSP22 of radial spokes [PMID: 7744782; PMID: 9585416]; Matsuo et al. 28 [PMID: 18334618] reported that the roc16 (rhythm of chloroplast) circadian rhythm mutant locus maps here; the mutation in CC-13
Cre01.g047950.t1.1 7 0 7 0 0 0 9.42 IFT27 IFT27; FAP156; Rabl4 IFT27 (FAP156), Intraflagellar Transport Protein 27; Rab-like GTPase (Qin et al. Rosenbaum 2007)(Follit et al. Pazour 2009)(Eguether et al. Pazour 2014)(Cole 2003)(Bhogaraju et al. Lorentzen 2011) IFT27  |  Small GTPase distantly related to Rab-like proteins from mammals, found in the flagellar proteome [PMID: 15998802]; belongs to core of IFT-B particle
Cre02.g089950.t1.2 7 0 7 0 0 0 8.36 IFT20 IFT20 IFT20, Intraflagellar Transport Protein 20 (Pazour et al. Besharse 2002)(Follit et al. Pazour 2009)(Cole 2003)(Follit et al. Pazour 2006) IFT20  |  Component of peripheral subcomplex of IFT-B particle
Cre10.g449250.t1.2 6 0 5 1 0 0 5.19 -1.67 KIFAP3 KAP1 KAP, Kinesin II Associated Protein 1 (Mueller et al. Porter 2005)(Cole et al. Rosenbaum 1997); Ciliary level increases during disassembly (Wang et al. Pan 2017) KAP1  |  Kinesin-associated protein; probable non-motor subunit of kinesin-II, the anterograde motor for intraflagellar transport.
Cre09.g394213.t1.1 6 0 2 3 1 0; Ger 9.71 TCTEX1D2 DLT4; Tctex2b DLT4 (Tctex2b), Dynein Light Chain; Associated with Inner Arm Dynein I1/f and Cytoplasmic Dynein 1b (DiBella et al. King 2004 )(Schmidts et al. Witman 2015)(Hom et al. King 2011) DLT4  |  Associated with Inner Arm Dynein I1/f and Cytoplasmic Dynein 1b
Cre01.g039200.t1.2 5 0 5 0 0 0 6.06 IFT22 IFT22; FAP9; Rabl5 IFT22 (FAP9), Intraflagellar Transport Protein 22; RAB-like GTPase (Follit et al. Pazour 2009)(Silva et al. Qin 2012); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT22  |  Flagellar Associated Protein, found in the Chlamydomonas flagellar proteome [PMID: 15998802]; belongs to core of IFT-B particle; has orthologs in most flagellated eukaryotes (RABL5 in human), a member of the Ras superfamily of GTPases but the GTP-specific
Cre04.g219250.t1.2 4 0 4 0 0 0 6.73 -1.62 IFT52 IFT52; BLD1; NGD5 IFT52, Intraflagellar Transport Protein 52 (Cole et al. Rosenbaum 1997)(Brazelton et al. Lefebvre 2001)(Pazour et al. Besharse 2002)(Follit et al. Pazour 2009)(Cole 2003)(Cole 2003); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT52  |  Component of core of IFT-B particle; contains ABC-type uncharacterized transport domain; mutated in bld1 mutant; the C. elegans homologue of IFT52/BLD1 is osm-6. [PMID: 11676918, PMID: 11676919, Genbank entry AF397450].
Cre12.g546400.t1.2 4 1 0 1 2 0 11.04 DYNLRB1; DYNLRB2 DLR2; DLC7b DLR2 (DLC7b), Roadblock/LC7 Family Light Chain; Found in Outer Arm Dynein, Cytoplasmic Dynein 1b, and Innner Arm Dynein I1/f (DiBella et al. King 2005 )(Hom et al. King 2011)(Schmidts et al. Witman 2015) DLR2  |  Found in Outer Arm Dynein, Cytoplasmic Dynein 1b, and Innner Arm Dynein I1/f; member LC7/Roadblock family; members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. LC7b inter
Cre10.g450350.t1.2 3 0 3 0 0 0 10.42 Hspb11 IFT25; FAP232; Hspb11 IFT25 (FAP232), Intraflagellar Transport Protein 25 (Keady et al. Pazour 2012)(Follit et al. Pazour 2009)(Lechtreck et al. Witman 2009)(Bhogaraju et al. Lorentzen 2011) IFT25  |  Found in the flagellar proteome [PMID: 15998802]; belongs to core of IFT-B particle; identified in the flagellar basal body proteome [PMID: 15137946]; upregulated by deflagellation
Cre16.g664500.t1.2 3 0 3 0 0 0 7.48 Arl6 BBS3; ARL6; ARFA1a; BBS3B BBS3 (ARL6 | ARFA1a), ADP-ribosylation factor 1; ARL6, ADP-Ribosylation Factor-Like Protein 6 (Mourao et al. Lorentzen 2014) BBS3  |  Flagellar ARF-like GTPase, most similar to mammalian ARL6; similar to mammalian BBS3 that, when mutated, causes Bardet-Biedl syndrome 3; ADP-ribosylation factor 1
Cre16.g664500.t2.1 3 0 3 0 0 0 7.48 Arl6 BBS3; ARL6; ARFA1a; BBS3B BBS3 (ARL6 | ARFA1a), ADP-ribosylation factor 1; ARL6, ADP-Ribosylation Factor-Like Protein 6 (Mourao et al. Lorentzen 2014) BBS3  |  Flagellar ARF-like GTPase, most similar to mammalian ARL6; similar to mammalian BBS3 that, when mutated, causes Bardet-Biedl syndrome 3; ADP-ribosylation factor 1
Cre07.g342200.t1.2 2 0 1 1 0 0 10.41 TTC30A IFT70; FAP259; Dyf-1; Fleer; Ttc30 IFT70 (FAP259 | Dyf-1 | Fleer), Intraflagellar Transport Protein 70 (Follit et al. Pazour 2009)(Howard et al. Maurer 2013)(Fan et al. Qin 201); Ciliary level increases during disassembly (Wang et al. Pan 2017) IFT70  |  Flagellar Associated coiled-coil protein; TPR protein found in the flagellar proteome as FAP259 [PMID: 15998802]; similar to dyf-1 (C. elegans); component of core of IFT-B particle; identified in the flagellar basal body proteome [PMID: 15137946]; upregul
Cre05.g241637.t1.1 2 0 2 0 0 0 8.93 -1.64 IFT46 IFT46; FAP32; ; CFAP32 IFT46 (FAP32), Intraflagellar transport protein 46 (Hou et al. Witman 2007)(Follit et al. Pazour 2009)(Cole 2003) IFT46  |  Flagellar Associated Protein; belongs to core of IFT-B particle
Cre06.g251200.t1.2 2 0 2 0 0 0 7.54 -1.15 IFT43 IFT43, MOT41 IFT43, Intraflagellar transport protein 43 (Cole 2003) IFT43  |  Component of IFT-A particle; identified by comparative genomics as being present only in organisms having motile cilia; this gene is in the location of Probe 2 used in PMID: 11805055
Cre06.g252000.t1.2 2 0 2 0 0 0 LZTFL1 LZTFL1, Leucine Zipper Transcription Factor Like 1 (Eguether et al. Pazour 2014) LZTFL1  |  NULL
Cre01.g004250.t1.2 1 0 1 0 0 0; Ger 7.34 DYNLT1; DYNLT2; DYNLT3; DLT3; TCTEX1 DLT3, Txtex1 Light Chain Associated with Inner Arm Dynein I1/f and Cytoplasmic Dynein 1b (Harrison et al. King 1998 )(Schmidts et al. Witman 2015)(Hom et al. King 2011) DLT3  |  Light Chain Associated with Inner Arm Dynein I1/f and Cytoplasmic Dynein 1b
Cre04.g219700.t1.1 1 0 1 0 0 0 3.14 BBS9 BBS9 BBS9, Bardet-Biedl syndrome 9 BBS9  |  Flagellar protein, component of the core BBSome complex that targets membrane proteins to cilia
Cre04.g219700.t2.1 1 0 1 0 0 0 3.14 BBS9 BBS9 BBS9, Bardet-Biedl syndrome 9 BBS9  |  Flagellar protein, component of the core BBSome complex that targets membrane proteins to cilia
Cre04.g219700.t3.1 1 0 1 0 0 0 3.14 BBS9 BBS9 BBS9, Bardet-Biedl syndrome 9 BBS9  |  Flagellar protein, component of the core BBSome complex that targets membrane proteins to cilia
Cre06.g267550.t1.2 1 0 1 0 0 0 4.83 BBS5 BBS5 BBS5, Bardet-Biedl syndrome 5 (Lechtrek et al. Witman 2009)(Li et al. Dutcher 2004) BBS5  |  Flagellar protein, component of BBSome that targets membrane proteins to cilia; probably mediates membrane association of the BBSome via its pleckstrin homology domain
Cre17.g722350.t1.2 1 0 1 0 0 0 RABL2 RABL2, RAB-Like GTP Binding Protein 2; IFT regulator (Nishijima et al. Nakayama 2017) RABL2  |  Distantly similar to a class of Rab-like proteins from mammals; IFT regulator
Cre01.g043750.t1.1 0 0 0 0 0 0 4.38 -1.17 BBS7 BBS7 BBS7, Bardot Biedl Syndrome 7 (Lechtrek et al. Witman 2009) BBS7  |  Flagellar protein, core component of the core BBSome complex that targets membrane proteins to cilia
Cre06.g257250.t1.1 0 0 0 0 0 0 BBS2 BBS2 BBS2, Bardot Biedl Syndrome 2 BBS2  |  Flagellar protein, component of the core BBSome complex that targets membrane proteins to cilia
Cre09.g394732.t1.1 0 0 0 0 0 0 CEP131 CEP131; AZI1 Cep131 (AZI1), Centrosomal Protein 131; BBSome Regulator CEP131  |  Identified by comparative genomics as being present only in organisms having motile (MOT) cilia; BBSome Regulator
Cre11.g467616.t1.1 0 0 0 0 0 0 8.53 -1.91 TTC26 IFT56; Dyf-13; Ttc26 Ift56 (Dyf-13 | Ttc26 ), Intraflagellar Transport Protein 56 (Ishikawa et al. Marshall 2014)(Follit et al. Pazour 2009) IFT56  |  TPR protein; belongs to core of IFT-B particle
Cre12.g487350.t1.2 0 0 0 0 0 0 1.64 CEP19 CEP19 CEP19, Centrosomal Protein 19; RABL2-binding protein (Nishijima et al. Nakayama 2017) CEP19  |  null-allele mutant was isolated (PMID 29743196); RABL2-binding protein
Cre12.g520650.t1.2 0 0 0 0 0 0 3.17 -1.03 TLP1 TLP1, Tubby-Like Protein 1 Tubby Family Transcription Factor (Thiriet-Rupert et al. Saint-Jean 2016); Putative Transcription Factor or Transcription Regulator (Riano-Pachonet al. Mueller-Roeber 2008) TLP1  |  NULL
Cre12.g548650.t1.1 0 0 0 0 0 0 2.8 -1.1 BBS4 BBS4 BBS4, Bardot Biedl Syndrome 4 (Lechtrek et al. Witman 2009) BBS4  |  Flagellar protein, peripheral BBsome component; interacts with the centriolar satellite protein PCM1 and recruits the entire BBSome complex to the centrosome
Cre16.g666500.t1.2 0 0 0 0 0 0 3.52 -1.26 TTC8 BBS8; TTC8 BBS8, Bardot Biedl Syndrome 8 (Lechtrek et al. Witman 2009) BBS8  |  Tetratricopeptide repeat domain protein, similar to human Bardet Biedl Syndrome 8; belongs to linker subcomplex of flagellar BBsome involved in targeting membrane proteins to the flagellum
Cre16.g667450.t1.2 0 0 0 0 0 0 2.4 -3.58 TLP2 TLP2, Tubby-Like Protein 2 Tubby Family Transcription Factor (Thiriet-Rupert et al. Saint-Jean 2016); Putative Transcription Factor or Transcription Regulator (Riano-Pachonet al. Mueller-Roeber 2008) TLP2  |  tubby-like protein 2. Transcript upregulated during flagellar regeneration [PMID: 15738400].
Cre17.g741950.t1.1 0 0 0 0 0 0 2.78 BBS1 BBS1 BBS1, Bardot Biedl Syndrome 1 (Lechtrek et al. Witman 2009) BBS1  |  Component of the core BBSome complex that targets membrane proteins to cilia