Central Apparatus
Info Page Total Peptides Axo Count M+M Count KCl Count Terg Count 30 Min DeFlag (Fold Δ) XAP5 (Fold Δ) Human Homolog Gene and Aliases ChlamyFPv5 Annotation References: Annotation v5.6 Description
Cre01.g025400.t1.2 60 37 0 4 19 11.2 HYDIN HYDIN; HYD3 HYD3, Hydrocephalus 3-Like Protein Hydin Component of the central apparatus (Lechtreck and Witman 2007); SPEF2- and HYDIN-mutant cilia lack the central pair associated protein SPEF2 aiding PCD diagnostics (Cindric and Omran 2019) HYDIN  |  hydrocephalus-inducing protein homolog, forms extension C2b of axonemal central pair
Cre03.g183200.t1.2 54 36 1 5 12 10.17 -2.3 SPEF2 CPC1 CPC1, Central Pair 1 Component of the central apparatus (Mitchell and Sale 1999)(Zhang and Mitchell 2004)(Mitchell et al. Mitchell 2005); SPEF2- and HYDIN-mutant cilia lack the central pair associated protein SPEF2 aiding PCD diagnostics (Cindric and Omran 2019) CPC1  |  Mutations at CPC1 disrupt assembly of a central pair microtubule-associated complex and alter flagellar beat frequency in Chlamydomonas [PMID: 15292403]. Identified in the flagellar and basal body proteome as FBB7 [PMID: 15137946]; upregulated by deflagel
Cre12.g519950.t1.1 47 37 0 4 6 9.42 -3.44 GUK1 FAP42; C1b-350; GUK3 FAP42, Flagellar Associated Protein 42; C1b-350 component of C1b projection on central pair C1b-350 component of C1b projection on central pair (Mitchell et al. Mitchell 2005) FAP42  |  Found in the flagellar proteome; contains N-terminal calpain cysteine endopeptidase domain; null-allele mutant was isolated (PMID 29743196); C1b-350 component of C1b projection on central pair
Cre10.g434400.t1.2 37 27 0 3 7 10.48 -1.82 none PF6 PF6, Central Pair Protein PF6 (Dutcher et al. Luck 1984) (Rupp et al. Porter 2001)(Wargo et al. Smith 2005) PF6  |  Together with C1a-86, C1a-34, C1a-32, C1a-18, and calmodulin, forms the central pair projection C1a; may play a role in modulating both inner and outer dynein arm activity
Cre02.g073750.t1.2 31 0 4 26 1 5.95 -1.52 KIF9 KLP1; KIN9-2 KLP1, Kinesin-Like Protein 1 Central apparatus protein (Bernstein et al. Rosenbaum 1984)(Yokoyama et al. Mitchell 2004) KLP1  |  Kinesin-like protein 1, kinesin-9 (Kif9) family; kinesin associated with one of the central pair microtubules of the flagellar axoneme
Cre10.g420800.t1.1 30 25 0 0 5 6.56 CFAP46 FAP46; C1d-HC2; CFAP46 FAP46, Flagellar Associated Protein 46; HC2 of C1d projection on central pair HC2 of C1d projection on central pair (DiPetrillo and Smith 2010) FAP46  |  Found in the flagellar proteome [PMID: 15998802]; together with FAP221,FAP54, FAP74, C1d-87 and calmodulin, form a single complex in the C1d projection NULL NULL FAP46 20421426 C1d-HC2 Flagellar Associated Protein 46
Cre08.g362100.t1.1 29 0 1 25 3 none FAP154 FAP154, PAS Sensory Domain Flagellar Associated Protein 154 Candidate Central Apparatus protein, co-immunoprecipitates as part of a complex with [FAP47, FAP49, FAP72, FAP416]; FAP49 is predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP154  |  Similar to Flagellar Associated Protein FAP154 with PAS sensory domain that was found in the flagellar proteome; null-allele passenger mutation was isolated (PMID 29743196)
Cre08.g362050.t1.2 27 0 0 21 6 none FAP49 FAP49, PAS Sensory Domain Flagellar Associated Protein 49 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule; co-immunoprecipitates as part of a complex with [FAP47, FAP72, FAP154, FAP416] (Zhao et al. Witman 2019) FAP49  |  Flagella Associated Membrane Protein with PAS sensory domain; found in the flagellar proteome [PMID: 15998802]; FAP153 likely is a part of FAP49.
Cre12.g513200.t1.2 26 2 13 9 2 -2.08 multiple PGH1; ENO Enolase (2-Phosphoglycerate Dehydratase) Component of the central apparatus (Mitchell et al. Mitchell 2005) PGH1  |  Phosphoenolpyruvate hydratase; 2-phosphoglycerate dehydratase; EC 4.2.1.11 [GI:18143, Dumont et al. (1993) Plant Sci. 89, 55-67]; product localization unsure: an N-terminal extension also found in Dunaliella and At1g74030 potentially targets it to an orga
Cre17.g704300.t1.1 24 17 0 0 7 10.5 -1.62 CFAP47 FAP47; CFAP47 FAP47, Flagellar Assoicated Protein 47; weakly Similar to Hydrocephalus 3 Central Apparatus protein, co-immunoprecipitates as part of a complex with [FAP49, FAP72, FAP154, FAP416]; FAP49 is predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP47  |  Flagellar Associated Protein; found in the flagellar proteome [PMID: 15998802]; identified in the flagellar basal body proteome [PMID: 15137946]; upregulated by deflagellation; weakly Similar to Hydrocephalus 3
Cre12.g518550.t1.1 22 21 0 0 1 6.52 -1.34 CFAP54 FAP54; C1d-HC1; CFAP54 FAP54, Flagellar Associated Protein 54; HC1 of C1d projection on central pair HC1 of C1d projection on central pair (DiPetrillo and Smith 2010); Mouse genetrap allele develops hydrocephalus, male infertility, and mucus accumulation (McKenzie et al. Lee 2015) FAP54  |  found in the flagellar proteome [PMID: 15998802]; identified in the flagellar basal body proteome [PMID: 15137946]; upregulated by deflagellation; together with FAP221, FAP46, FAP74, C1d-87 and calmodulin, form a single complex in the C1d projection; HC1
Cre03.g168200.t1.2 20 16 0 0 4 8.39 -2.17 CFAP69 FAP69; C1b-135; CFAP69 FAP69, Flagellar Associated Protein 69; C1b-135 component of C1b projection on central pair C1b-135 component of C1b projection on central pair (Mitchell et al. Mitchell 2005); Mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagella (Dong et al. Coutton 2018) and (He et al. Cao 2018); Major cause of infertility in humans Mbagano et al. Toure 2019) FAP69  |  Conserved Flagellar Associated Protein
Cre07.g354551.t1.2 20 0 0 20 0 8.8 -2.84 CFAP65 FAP65; CFAP65; AKAP240 FAP65, Flagellar Associated Protein 65 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019); AKAP240, A-kinase anchoring protein (D'Souza et al. Yang abstract #84 from Chlamy 2014, but not in Rao et al. D'Souza 2016); Homozygous nonsense mutation was found in a male with infertility (Tang et al. Zhang 2017); Biallelic mutations lead to severe asthenoteratospermia due to acrosome hypoplasia and flagellum malformations (Wang et al. Tan 2019); Biallelic mutations in CFAP65 cause male infertility with multiple morphological abnormalities of the sperm flagella in humans and mice (Li et al. Zhang 2019); A novel homozygous CFAP65 mutation in humans causes male infertility with multiple morphological abnormalities of the sperm flagella (Zhang et al. Yang 2019) FAP65  |  NULL
Cre03.g167600.t1.2 19 16 0 1 2 11.39 -2.81 CFAP61 FAP61; CaM-IP3; CFAP61 FAP61, Flagellar Associated Protein 61; CaM-IP3; Associated with the CaM- and spoke-Associated CSC complex at the base of the radial spoke; altered in DRC mutant axonemes; conserved CaM-IP3, associated with the CaM- and spoke-associated CSC complex at the base of the radial spoke (Dymek and Smith 2007); altered in DRC mutant axonemes ( Lin et al. Nicastro 2011); conserved; basal structure of RS3 (Urbanska et al Wloga 2015) FAP61  |  Associated with the CaM- and spoke-Associated CSC complex at the base of the radial spoke; altered in DRC mutant axonemes; conserved Flagellar Associated Protein; identified in the flagellar basal body proteome [PMID: 15137946]; basal structure of RS3 (Pu
Cre07.g345400.t1.2 19 0 1 18 0 12.48 -1.7 CFAP70 FAP70; CFAP70 FAP70, Flagellar Associated Protein 70 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019); Localizes at the base of the outer dynein arm and Chlamy mutants have ODA-like phenotypes. CFAP70 localizes to motile mouse cilia. (Shamoto et al. Takeda 2018) FAP70  |  Conserved uncharacterized Flagellar Associated Protein; found in the flagellar proteome [PMID: 15998802]
Cre04.g224250.t1.1 18 1 0 15 2 14.93 -2.56 MYCBPAP FAP147 FAP147, Flagellar Associated Protein 147; weakly Similar to Myc-Binding Protein-Associated Protein Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP147  |  Flagellar Associated Protein weakly similar to Myc-binding protein-associated protein; found in the flagellar proteome; identified by comparative genomics as being present only in organisms having motile cilia; gene conserved only in orga
Cre06.g271150.t1.1 18 15 0 0 3 9.08 -1.82 CFAP74 FAP74; C1d-HC3; CFAP74 FAP74, Flagellar Associated Protein 74; HC3 of C1d projection on central pair HC3 of C1d projection on central pair (DiPetrillo and Smith 2010) FAP74  |  found in the flagellar proteome [PMID: 15998802]; HC3 of C1d projection on central pair (PubMed ID:20421426 DiPetrillo and Smith, 2010); together with FAP221, FAP46, FAP54, C1d-87 and calmodulin, form a single complex in the C1d projection
Cre06.g296850.t1.2 18 12 0 0 6 9.51 -1.44 DLEC1 FAP81; Dlec1; CFAP81 FAP81, Flagellar Associated Protein 81; Similar to DLEC1 deleted in lung and esophageal cancer 1 Candidate Central Apparatus protein, predicted to be associated with the C1a or C1e projection (Zhao et al. Witman 2019) FAP81  |  Similar to DLEC1 deleted in lung and esophageal cancer 1
Cre03.g185650.t1.2 17 13 0 0 4 11.85 -1.9 WDR66 FAP251; CaM-IP4; CFAP251; WDR66 FAP251, Flagellar Associated Protein 251; CaM-IP4; Associated with the CaM- and spoke-Associated CSC complex at the base of the radial spoke CaM-IP4, associated with the CaM- and spoke-associated CSC complex at the base of the radial spoke (Dymek and Smith 2007); basal structure of RS3 (Urbanska et al. Wloga 2015); mutations lead to male infertility in humans (Auguste et al. Mitchell 2018)(Li et al. Cao 2018); Major cause of infertility in humans Mbagano et al. Toure 2019) FAP251  |  Flagellar Associated Protein; found in the flagellar proteome; identified in the flagellar basal body proteome [PMID: 15137946]; upregulated by deflagellation; associated with the CaM- and spoke-Associated CSC complex at the base of the radial spoke
Cre06.g249900.t1.2 17 0 0 17 0 14.81 -2.11 AK7 FAP75 FAP75, P-Loop Flagellar Associated Protein 75 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP75  |  Flagellar Associated Protein containing P-loop, found in the flagellar proteome [PMID: 15998802]; null-allele mutant was isolated (PMID 29743196)
Cre12.g531800.t1.1 17 3 1 4 9 7.29 -1.57 none FAP7 FAP7, Flagellar Associated Protein 7 Candidate Central Apparatus protein (Zhao et al. Witman 2019) FAP7  |  Flagellar Associated Protein, found in the flagellar proteome [PMID: 15998802]
Cre08.g362000.t1.2 16 0 0 13 3 -1.7 none FAP72 FAP72, Flagellar Associated PAS Domain Protein 72 Candidate Central Apparatus protein, co-immunoprecipitates as part of a complex with [FAP47, FAP49, FAP154, FAP416]; FAP49 is predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019); It is likely that the phytozome models for FAP408 and FAP72 represent the 5' and 3' ends of the same gene FAP72  |  Flagellar Associated Protein, found in the flagellar proteome [PMID: 15998802]
Cre09.g387689.t1.1 16 13 0 0 3 10.22 CCDC180 FAP76; CCDC180 FAP76, Flagellar Associated Protein 76; Similar to human CCDC180 Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019); human homologue is CCDC180; Cell Cycle Gene (Breker Lieberman and Cross 2018) FAP76  |  Flagellar Associated Protein, found in the flagellar proteome [PMID: 15998802]
Cre02.g145100.t1.1 15 0 2 7 6 ATP2B3 FAP39; CFAP39 FAP39, Flagellar Associated Protein 39; Similar to Ca2+-Transporting ATPase Candidate Central Apparatus protein, predicted to be associated with the C1b or C1f projection (Zhao et al. Witman 2019) FAP39  |  Flagellar Associated Protein; found in the flagellar proteome; similar to Ca2+ transporting ATPase; related to cation transporting ATPase; plasma membrane calcium-transporting ATPase 3 (PMCA3) (Plasma membrane calcium pump isoform 3). Po
Cre08.g372100.t1.2 15 10 2 2 1 -1.45 multiple HSP70; HSP70A HSP70A, Heat Shock 70 kDa Protein Central apparatus protein (Mitchell et al. Mitchell 2005)(Shapero et al. Johnson 2005); Transition Zone Protein (16 spectral counts [Diener et al. Rosenbaum 2015]) HSP70A  |  HSP70A is one of 9 genes encoding HSP70-like proteins in Chlamydomonas; HSP70A is localized to the cytosol and to flagella; it is inducible by heat shock and light [PMID: 2779571, 1541398, 16151252, 16143837]. Found in the flagellar proteome [PMID: 159988
Cre04.g227900.t1.2 14 0 1 11 2 13.1 -2.61 SPAG16 PF20 PF20, Central Pair Associated WD-Repeat Protein (Smith and Lefebvre 1997) PF20  |  WD-repeat containing protein PF20 of the central pair of the flagella; associates with the intermicrotubule bridge; may contain additional coding sequence in intronic N-island PMID: 27175017
Cre12.g546100.t1.1 14 7 0 3 4 3.99 -3.03 KIF3B FAP125 FAP125, Flagellar Associated Protein 125; Similar to Kinesin KIF17 Candidate Central Apparatus protein (Zhao et al. Witman 2019) FAP125  |  kinesin-14 (C-terminal motor) family; Similar to Kinesin KIF17; Flagellar Associated Protein found in the flagellar proteome
Cre11.g476376.t1.1 13 12 0 0 1 8.7 CFAP221 FAP221; Pcdp1; CFAP221 FAP221, Coiled-Coil Flagellar Associated Protein 221; HC4 of C1d projection on central pair; very Similar to FAP360 - not clear if this is a recent gene duplicatoin or an assembly artifact; Similar to mammalian primary ciliary dyskinesia protein 1 (Pcdp1) Pcdp1: HC4 of C1d projection on central pair (DiPetrillo and Smith 2010); Identification of genetic variants in CFAP221 as a cause of primary ciliary dyskinesia (Bustamante-Marin and Zariwala 2019) FAP221  |  HC4 of C1d projection on central pair; Similar to mammalian primary ciliary dyskinesia protein 1 (Pcdp1); this gene model is probably a fusion between RNA polymerase III subunit RPC82 and a protein very similar to FAP221 Cre49.g761347, probably due to an
Cre12.g546100.t2.1 13 7 0 2 4 3.99 -3.03 KIF3B FAP125; KIN14-2 FAP125, Flagellar Associated Protein 125; Similar to Kinesin KIF17 Candidate Central Apparatus protein (Zhao et al. Witman 2019) FAP125  |  kinesin-14 (C-terminal motor) family; Similar to Kinesin KIF17; Flagellar Associated Protein found in the flagellar proteome
Cre13.g562250.t1.1 13 10 0 0 3 14.81 -2.06 none FAP92 FAP92, Flagellar Associated Protein 92 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019) FAP92  |  Flagellar Associated Protein, found in the flagellar proteome [PMID: 15998802]
Cre14.g624400.t1.2 12 7 0 0 5 5.19 -2.17 CFAP99 FAP99; CFAP99 FAP99, Flagellar Associated Protein 99 Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019) FAP99  |  Flagellar Associated Protein, found in the flagellar proteome [PMID: 15998802]
Cre06.g256450.t1.2 11 8 0 2 1 11.85 -2.53 CCDC189 FAP119; C1a-34; PF6-IP2 FAP119, Flagellar Associated Protein 119; C1a-34; C1a projection on central pair C1a-34, C1a projection on central pair (Wargo et al. Smith 2005); pI shift in DRC mutants (Lin et al. Nicastro 2011); Ciliary level increases during disassembly (Wang et al. Pan 2017) FAP119  |  also known as C1a-34; form the C1a projection, with PF6, C1a-86, C1a-32, C1a-18, and calmodulin; similar to C1a-32; may play a role in modulating both inner and outer dynein arm activity; pI shift in DRC mutants (PubMed ID:21700706 Lin et al. Nicastro 20
Cre06.g297200.t1.2 11 0 0 1 10 7.21 -2.34 CTCF FAP108 FAP108, Flagellar Associated Protein 108 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019) FAP108  |  Flagellar Associated Protein, found in the flagellar proteome
Cre07.g330700.t1.2 11 6 0 0 5 5.27 -2.28 MAATS1 FAP91; Cam-IP2; CFAP91 FAP91, Flagellar Associated Protein 91; Cam-IP2; Associated with the CaM- and spoke-Associated CSC complex at the base of the radial spoke; Similar to Sperm cAMP-Dependent Protein Kinase Associated Protein AAT1 Cam-IP2, associated with the CaM- and spoke-associated CSC complex at the base of the radial spoke (Dymek and Smith, 2007) FAP91  |  Flagellar Associated Protein similar to sperm protein kinase associated protein AAT1. Found in the flagellar proteome, upregulated by deflagellation [PMID: 15998802]; identified in the flagellar and basal body proteome as FBB8 [PMID: 15137946]; Associated
Cre09.g389282.t1.1 11 4 0 0 7 7.34 -2.39 CCDC189 FAP114; C1a-32; PF6-IP3 FAP114, Coiled-Coil Flagellar Associated Protein 114; C1a-32; C1a projection on central pair C1a-32, C1a projection on central pair (Wargo et al. Smith 2005); Ciliary level increases during disassembly (Wang et al. Pan 2017) FAP114  |  also known as C1a-32; forms the C1a projection, with PF6, C1a-86, C1a-34, C1a-18, and calmodulin; similar to C1a-34; may play a role in modulating both inner and outer dynein arm activity
Cre14.g618750.t1.1 11 10 0 0 1 13.53 -1.88 LRGUK FAP246; CFAP246 FAP246, Leucine-Rich Repeat Flagellar Associated Protein 246 Central Apparatus protein, predicted to be associated with the C1b or C1f projection (Zhao et al. Witman 2019) FAP246  |  Calpain cystein protease and Flagellar Associated Protein, found in the flagellar proteome. Possibly an adenylate cyclase
Cre49.g761347.t1.1 11 9 0 0 2 11.2 CFAP221 FAP360; FAP221L; Pcdp1 FAP360, Flagellar Associated Protein 360; very similar to FA221 - not clear if this is a recent gene duplication or an assembly artifact; Similar to mammalian primary ciliary dyskinesa protein 1 (Pcdp1) FAP360  |  flagella protein of the C1d central pair projection; similar to PRIMARY CILIARY DYSKINESIA PROTEIN 1 (PCDP1); bind calmodulin in high CA2+; N-terminus is homologous to that of Hydin; very Similar to FAP221 - not clear if this is a recent gene duplicatoin
Cre02.g112100.t1.1 10 6 0 0 4 6.69 -1.31 TCTE1 FAP101; C1a-86; PF6-IP1 FAP101, Flagellar Associated Protein 101; C1a-86; C1a projection on central pair C1a-86 , C1a projection on central pair (Wargo et al. Smith 2005) FAP101  |  Flagellar Associated Protein with weak similarity to a kinase regulatory subunit; also known as C1a-86; form the C1a projection, with PF6, C1a-34, C1a-32, C1a-18, and calmodulin; may play a role in modulating both inner and outer dynein arm activity
Cre03.g171800.t1.2 10 1 0 0 9 3.53 -2.37 ODF3B FAP123 FAP123, Flagellar Associated Protein 123 Candidate Central Apparatus protein (Zhao et al. Witman 2019) FAP123  |  Flagellar Associated Protein, found in the flagellar proteome
Cre09.g387912.t1.1 10 0 0 8 2 -2.09 CROCC FAP139 FAP139, Coiled-Coil Flagellar Associated Protein 139; serine endopeptidase Candidate Central Apparatus protein (Zhao et al. Witman 2019) FAP139  |  NULL
Cre12.g511750.t1.2 9 3 0 0 6 5.49 none FAP105 FAP105, Flagellar Associated Protein 105 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019); Ciliary level increases during disassembly (Wang et al. Pan 2017) FAP105  |  NULL
Cre03.g178150.t1.1 8 2 2 2 2 2.83 CALM2 CAM1; RSP20 CAM1, Calmodulin 1; Radial Spoke Component Radial Spoke Subunit (Wargo et al. Smith 2005)(Yang et al. Witman 2006); Transition Zone Protein (4 spectral counts [Diener et al. Rosenbaum 2015]) CAM1  |  identical to CALM_CHLRE; contains 4 EF-hand, calcium binding motifs; Calmodulin mediates the control of a large number of enzymes by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatas
Cre09.g394251.t1.1 8 3 0 5 0 12.13 -2.36 SPAG6 PF16 PF16, Central Pair Protein PF16 (Dutcher et al. Luck 1984)(Smith and Lefebvre 1996) PF16  |  NULL
Cre17.g724550.t1.2 8 0 2 3 3 6 SSNA1 DIP13; NA14 DIP13, Deflagellation Inducible Protein; 13KD; Similar to Sjoegren syndrome nuclear autoantigen Candidate Central Apparatus protein (Zhao et al. Witman 2019); (Pfannenschmid et al. Mages 2003); Centriolar Protein (Hamel et al. Gonczy 2017) DIP13  |  Deflagellation inducible protein, 13 kDa [gi:4689324, PMID: 12643]; found in the flagellar proteome; similar to Sjogren's syndrome nuclear autoantigen 1; 13KD
Cre02.g105950.t1.2 7 5 0 2 0 9.63 -1.42 MYCBP FAP174 FAP174, Flagellar Associated Protein 174; AKAP interactor in the central pair Predicted to be associated with the C2 microtubule (Rao et al. D'Souza 2016) but co-immunoprecipitates as part of a complex with the C1b proteins CPC1, FAP42, FAP69, HSP70A and Enolase, together with the central apparatus protein FAP246 and the candidate central apparatus protein FAP39, suggesting association with either the C1b projection or the C2b projection with which C1b interacts (Zhao et al. Witman 2019); AKAP interactor in the central pair (Rao et al. D'Souza 2016). FAP174  |  MYCBP-1 homolog; AKAP interactor in the central pair; found in the flagellar proteome, interacts with AKAP240 to regulate ciliary beating
Cre11.g482300.t1.2 7 3 0 0 4 6.27 SPATA17 FAP305; MOT17 FAP305, Flagellar Associated Protein 305; Similar to SPAG17 Candidate Central Apparatus protein, predicted to be associated with the C1a or C1e projection (Zhao et al. Witman 2019) FAP305  |  identified by comparative genomics as being present only in organisms having motile (MOT) cilia; Similar to SPAG17
Cre12.g522150.t1.1 7 3 0 3 1 5.44 -1.19 SPAG6 FAP194 FAP194, Flagellar Associated Protein 194; Similar to Central Pair Protein PF16 Candidate Central Apparatus protein (Zhao et al. Witman 2019); Ciliary level increases during disassembly (Wang et al. Pan 2017) FAP194  |  Armadillo-repeat protein, similar to PF16; found in the flagellar proteome
Cre17.g729850.t1.2 7 2 0 1 4 9.51 MORN2 FAP227; C1a-18; PF6-IP4 FAP227, Flagellar Associated Protein 227; C1a-18, C1a projection on central pair; Similar to Testis Specific Gene A2 C1a-18, C1a projection on central pair (Wargo et al. Smith 2005) FAP227  |  Similar to Testis Specific Gene A2; Together with PF6, C1a-86, C1a-34, C1a-32 and calmodulin, forms the central pair projection C1a; may play a role in modulating both inner and outer dynein arm activity; Similar to Sjoegren syndrome nuclear autoantigen
Cre10.g418150.t1.2 6 0 0 4 2 9.34 SPATA4 FAP178 FAP178, Flagellar Associated Protein 178; Similar to Testis and Spermatogenesis Cell Related Protein 2 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP178  |  Flagellar Associated Protein, found in the flagellar proteome; Similar to Testis and Spermatogenesis Cell Related Protein 2
Cre10.g418150.t2.1 6 0 0 4 2 9.34 SPATA4 FAP178 FAP178, Flagellar Associated Protein 178; Similar to Testis and Spermatogenesis Cell Related Protein 2 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP178  |  Flagellar Associated Protein, found in the flagellar proteome; Similar to Testis and Spermatogenesis Cell Related Protein 2
Cre14.g624900.t1.2 6 1 0 4 1 15.78 none FAP171 FAP171, Flagellar Associated Protein 171 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP171  |  Flagellar Associated Protein, found in the flagellar proteome
Cre14.g630200.t1.2 6 0 0 6 0 4.96 -1.68 none FAP312 FAP312, Flagellar Associated Protein 312 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP312  |  NULL
Cre14.g630200.t2.1 6 0 0 6 0 4.96 -1.68 none FAP312 FAP312, Flagellar Associated Protein 312 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP312  |  NULL
Cre16.g690450.t1.1 6 0 0 5 1 8.84 -2.73 RSPH10B FAP266 FAP266, Flagellar Associated Protein 266 Candidate Central Apparatus protein (Zhao et al. Witman 2019) FAP266  |  Conserved uncharacterized Flagellar Associated Protein; found in the flagellar proteome
Cre01.g051050.t1.2 5 0 0 2 3 5.76 -3.03 PPEF1 FAP225 FAP225, Flagellar Associated Protein 225 Candidate Central Apparatus protein (Zhao et al. Witman 2019) FAP225  |  Flagellar Associated Protein, found in the flagellar proteome
Cre03.g145387.t1.1 5 0 0 3 2 3.63 -2.24 FAM228A FAP239 FAP239, Coiled-Coil Flagellar Associated Protein 239 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP239  |  NULL
Cre05.g239200.t1.2 5 2 0 1 2 4.19 -2.83 none FAP275 FAP275, Flagellar Associated Protein 275 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019) FAP275  |  Flagellar Associated Protein, found in the flagellar proteome
Cre15.g640000.t1.1 4 2 0 0 2 1.91 -1.17 none FAP345 FAP345, Flagellar Associated Protein 345 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019); Ciliary protein (Lin et al. Dutcher 2018) FAP345  |  NULL
Cre16.g693204.t1.1 4 1 0 0 3 10.49 none FAP348 FAP348, Flagellar Associated Protein 348 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019) FAP348  |  NULL
Cre01.g010400.t1.2 3 0 1 0 2 1.82 FAP380 FAP380, Flagellar Associated Membrane Protein 380 Candidate Central Apparatus protein (Zhao et al. Witman 2019); Ciliary level increases during disassembly (Wang et al. Pan 2017); Transition Zone Protein (3 spectral counts [Diener et al. Rosenbaum 2015]) FAP380  |  NULL
Cre12.g497200.t1.2 3 1 0 0 2 6.64 -2.62 RNF39 FAP216 FAP216, EF-Hand Flagellar Associated Protein 216 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019) FAP216  |  Flagellar Associated Protein, found in the flagellar proteome
Cre01.g009800.t1.2 2 2 0 0 0 4.48 -2.87 ACIN1 FAP289 FAP289, Coiled-Coil Flagellar Associated Protein 289 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019) FAP289  |  Found in the flagellar proteome; transcript upregulated during flagellar regeneration [PMID: 157384]
Cre01.g029350.t1.2 2 1 0 0 1 6.83 -1.65 WDR93 FAP297; C1d-87 FAP297, WD40-Repeat Containing Coiled-Coil Flagellar Associated Protein 297; C1d-87 projection on central pair C1d-87 projection on central pair (Brown et al. Witman 2012) FAP297  |  contains WD40 repeats; found in the flagellar proteome [PMID: 15998802]; together with FAP221, FAP46, FAP54, FAP74 and calmodulin, form a single complex in the C1d projection
Cre08.g362019.t1.1 1 0 0 1 0 -2.76 FAP408 FAP408, Flagellar Associated Membrane Protein with PAS Sensory Domain 408; likely this encodes the N-terminus of FAP72 Possibly an assembly artifact; 100% identical to the N-terminus of the NCBI model for FAP72, which is missing from the Phytozome model for FAP72 FAP408  |  NULL
Cre08.g364000.t1.1 1 0 1 0 0 -1.34 FAP413 FAP413, Flagellar Associated Protein 413 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019)  |  NULL
Cre09.g394065.t1.1 1 0 1 0 0 FAP414 FAP414, Flagellar Associated Protein 414 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019)  |  NULL
Cre09.g409600.t1.1 1 1 0 0 0 4.14 -2.13 FAP411 FAP411, Flagellar Associated Protein 411 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019)  |  NULL
Cre12.g497450.t1.2 1 0 1 0 0 7.74 -1.56 FAP412 FAP412, Flagellar Associated Protein 412 Candidate Central Apparatus protein, predicted to be associated with the C1 microtubule (Zhao et al. Witman 2019)  |  NULL
Cre12.g509800.t1.2 1 0 0 1 0 7.15 -3.26 GOLGA8A FAP286 FAP286, Coiled-Coil Flagellar Associated Protein 286 Candidate Central Apparatus protein, predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019) FAP286  |  Flagellar Associated Coiled-Coil Protein; found in the flagellar proteome; transcript upregulated during flagellar regeneration [PMID: 157384]
Cre17.g697750.t1.2 1 0 0 0 1 6.6 FAP416 FAP416, Flagellar Associated Protein 416 Candidate Central Apparatus protein, co-immunoprecipitates as part of a complex with [FAP47, FAP49, FAP72, FAP154]; FAP49 is predicted to be associated with the C2 microtubule (Zhao et al. Witman 2019)  |  NULL
Cre03.g176833.t1.1 0 0 0 0 0 46.1 NAP1; DII5 NAP1 (DII5), novel actin-related protein that can substitute for actin in Inner Arm Dyneins b and g. Candidate Central Apparatus protein, predicted to be associated with the C1a or C1e projection (Zhao et al. Witman 2019); (Hom et al. King 2011); Component of the cell body actin cytoskeleton (Craig et al. Avasthi 2010) NAP1  |  Monomeric inner arm axonemal protein that can functionally replace actin for species b and g assembly; expression is activated in conventional actin (ida5) mutants [PMID: 97999]; nap1 null mutants are sensitive to the actin depolymerizing drug Latrunculin
Cre06.g279100.t1.2 0 0 0 0 0 5.59 DPY30 DPY30, Flagellar Associated Protein with Dpy-30 motif Central Apparatus protein, predicted to be associated with the C1a or C1e projection (Zhao et al. Witman 2019) DPY30  |  Chromatin modifying protein complex member, identified by mutations in C. elegans defective in male sensory behavior. Identified in the flagellar and basal body proteome as FBB12 [PMID: 15137946]. Transcript upregulated during flagellar regeneration [PMID
Cre10.g429750.t1.1 0 0 0 0 0 FAP417 FAP417, Flagellar Associated Protein 417 Candidate Central Apparatus protein (Zhao et al. Witman 2019) NULL  |  NULL
Cre10.g454600.t1.1 0 0 0 0 0 FAP415 FAP415, Flagellar Associated Protein 415 Candidate Central Apparatus protein (Zhao et al. Witman 2019) NULL  |  NULL
© Gregory J. Pazour