The Chlamydomonas Flagellar Proteome Project
ChlamyFPv5 (gene name | annotation): DRC2 | "DRC2 (FAP250), dynein regulatory complex 2; Similar to NYD-SP28"
Aliases: DRC2; FAP250; CCDC65; IDA6; CFAP250
Structure: Dynein Regulatory Complex
References: "(Bower et al. Porter 2013)( Lin et al. Nicastro 2011); pf3, conserved; methylated (Werner-Peterson and Sloboda 2013); PCD (Austin-Tse et al Hildebrandt 2013); Mutations disrupt the assembly of several other N-DRC subunits and also destabilizes the assembly of several closely associated structures such as the inner dynein arms, the radial spokes, and the calmodulin- and spoke-associated complex (Bower et al Porter 2018)"
CrFP Total Peptides = 17 (12 Axonemal Peptides | 0 M+M Peptides | 0 KCl Peptides | 5 Tergitol Peptides)
Wang Peptides (Wang et al. Pan 2017) = 6 (enriched 1 fold by ciliary shortening)
Jordan Peptides (Jordan et al. Pigino 2018) = Wild Type M+M: 0 | Dhc1b-3 M+M: 0 | Ift139-2 M+M: 1 (Total Unique Peptides)
Picariello Peptides (Picariello et al. Witman 2019) = Wild Type M+M: 2 | Ift140 ΔN-terminal WD repeat M+M: 9 (Total Unique Peptides)
Phytozome (gene name | defline): DRC2 | Flagellar Associated Protein
Annotation v5.6 Symbol | Defline: DRC2 | dynein regulatory complex 2
Annotation v5.6 Description: Flagellar Associated Protein; found in the flagellar proteome; identified in the flagellar basal body proteome [PMID: 15137946]; upregulated by deflagellation; Similar to NYD-SP28
Annotation v5.6 Synonyms: FAP250#Cre13.g607750.t1.1#g14651.t1
Steve King Dynein Anotation: (no data) | (no data)
Yuqing Hou's Human Homologs: CCDC65, NP_149115.2, coiled-coil domain-containing protein 65 [Homo sapiens] (Blast E value: 0 | Reprocal Best Match? Yes)
Albee et al. Dutcher 2013 Human Homolog: CCDC65, coiled-coil domain-containing protein 65
Lipid Modifications (N-Myristoylation: MGXXXS/T, S-Geranylgeranylation: CAAX , S-Geranylgeranylation: CC/CXC, S-Farnesylation: CAAX predicted by GPS-Lipid): (no data)
Fold Upregulated Post Deflagellation (Albee et al. Dutcher 2013) at 3 min: 6.75; at 10 min: 13.59; at 30 min: 7.88; at 60 min: 2.09
Importance of XAP5 for expression (Li et al. Hu 2018) Wild Type: (no data) FPKM | XAP Mutant: (no data) FPKM | Fold Change: (no data)
CLIP Library: Cre13.g607750
Phytozome Transcript: Cre13.g607750.t1.2
PhosphoPeptides
Protein Reference Source Peptide pLOGO
ChlamyFP Peptides
Fraction Sequence
(click on peptide to see other models containing this peptide)
T03QLVEVQVVSR
T03QYLDGISVNDDVLNNPVNPLLVVNNR
T03IQLEGIIEELEK
T03AALKIER
T03AYLESTEHR
A22AAAATGAGLSVTGQGAGGGGQK
A22ALEAEFAADLK
A22QLSLASSGAMETLR
A22ALEDEFETERTEIVNAHTR
A22IQLEGIIEELEKSFELAHR
A22ALEDEFETER
A22ASMPEDSSKEAPGPSK
A22LAVAENVLK
A22LQITLTER
A22EIEILSQNHER
A21ASMPEDSSK
A21DAIMQMLDRDLEEAEEQYSLAVR
© Gregory J. Pazour