The Chlamydomonas Flagellar Proteome Project
ChlamyFPv5 (gene name | annotation): FAP44 | "FAP44, Flagellar Associated Protein 44; part of tether complex that constrains inner arm I1/f"
Aliases: FAP44; CFAP44
Structure:
References: "Part of tether complex that constrains inner arm I1/f (Kubo et al. Oda 2018; Fu et al. Nicastro 2018; Urbanska et al. Wloga 2018) Mutations cause loss of central pair in spermatozoa (Tang et al. Zhang 2017); Mutant mice and humans have sperm defects Coutton et al. Ray 2018)"
CrFP Total Peptides = 45 (5 Axonemal Peptides | 0 M+M Peptides | 34 KCl Peptides | 6 Tergitol Peptides)
Wang Peptides (Wang et al. Pan 2017) = 36 (enriched 1.19 fold by ciliary shortening)
Phytozome (gene name | defline): FAP44 | Flagellar Associated Protein
O. Vallon Gene Name | Defline: FAP44 | Flagellar Associated Protein 44
O. Vallon Description: Flagellar Associated Protein, found in the flagellar proteome [PMID: 15998802]; part of tether complex that constrains inner arm I1/f
O. Vallon Synonyms: g9118.t1#Cre29.g778250.t1.1
Steve King Dynein Anotation: |
Yuqing Hou's Human Homologs: CFAP44, NP_060808.2, WD repeat-containing protein 52 isoform 2 [Homo sapiens] (Blast E value: 2.00E-73 | Reprocal Best Match? Yes)
Albee et al. Dutcher 2013 Human Homolog: WDR52, WD repeat-containing protein 52 isoform 1
Lipid Modifications (N-Myristoylation: MGXXXS/T, S-Geranylgeranylation: CAAX , S-Geranylgeranylation: CC/CXC, S-Farnesylation: CAAX predicted by GPS-Lipid):
Fold Upregulated Post Deflagellation (Albee et al. Dutcher 2013) at 3 min: 3.49; at 10 min: 7.94; at 30 min: 9.1; at 60 min: 2.84
Importance of XAP5 for expression (Li et al. Hu 2018) Wild Type: 236.54 FPKM | XAP Mutant: 46.63 FPKM | Fold Change: -2.34
CLIP Library: Cre09.g386736
Phytozome Transcript: Cre09.g386736.t1.1
PhosphoPeptides
Protein Reference Source Peptide pLOGO
ChlamyFP Peptides
Fraction Sequence
(click on peptide to see other models containing this peptide)
T27AAAAASAAAGGEGGAGGRDTDAR
T27KGLFADPVQQR
T26FGQVIDLELLDRVSSSR
T26AAVVAELDAVVPESDPFREALVR
T26RAAVVAELDAVVPESDPFREALVR
T25LLVGLQELQLLR
C08KAAAAAAGGLGGFAGAAAGPK
C08KPAAGGAAPAGGALAGGAAGSGSVAHGAGGPSAGGQQGLTAAEEALAK
C08AAAAAAGGLGGFAGAAAGPK
C08DALVALVNAQAAELDRLK
C08LAEATAALEEGTASGK
C08LKSDPNYVVPEEER
C08LAEATAALEEGTASGKLNK
C08VDELEEEKAGLR
C08LVEQGLAAVNADMAEFQKEK
C08WVVADKAGNVYTVALPPAGPVGK
C08ARPGPASAGPAVYIYSYPGLEVVK
C08TLPPPAPPPSLPPASAASSGVAQLLSVHGLDTHR
C08TLLAVGEK
C08ELAEWDAK
C07AAAAASAAAGGEGGAGGR
C07EAVTDADLAAFAAR
C07MWDFGAVNDAEPR
C07DGGGVGAVAVHPSR
C07MMAAVPQSELEK
C07LALLGSGDGLVR
C07LELAWESER
C06LAMLELEEALHDIAAAFNAK
C06VASHPAGAVAGLQLSAR
C06GDTLASVGHFPDFLLTLWDWR
C06RLAMLELEEALHDIAAAFNAK
C06GSDTGGGPGGDAAAR
C06LESGLTATR
C06VLSAGADGR
C06CTPEGPCSAVPDGEPR
C06RLELEGLVAR
C06FGQVIDLELLDR
C06LGLEADVK
C06AGNVYTVALPPAGPVGK
C06GLFADPVQQR
A07MDELVVLTR
A07AEFEALLAENEAAPEALRLPR
A07RLESGLTATR
A07ADLEVDPGLR
A06SKLSEEITAMLDAFDDAHSALKAEK